About Company
Career.zycto is devoted to linking pioneering scientific minds with transformative research endeavors. For a Structural Biologist, our platform provides an unparalleled route to projects that extend the boundaries of molecular understanding, drug discovery, and biotechnological innovation. We advocate for an environment where precision aligns with purpose, empowering you to apply your expertise in macromolecular structure determination to solve real-world challenges. Join us to become part of a dynamic ecosystem that values scientific exactitude, a cooperative ethos, and the relentless pursuit of knowledge. Career.zycto ensures your next professional step is not merely a job, but a crucial stride in shaping the future of life sciences.
Job Description
Are you a highly motivated and detail-oriented Structural Biologist ready to make a significant impact in the field of biotechnology? Career.zycto is thrilled to partner with a leading research and development organization in Tupelo, MS, seeking an exceptional individual to join their innovative team. This full-time position offers a unique opportunity to delve into complex biological systems, utilizing cutting-edge techniques to unravel the mysteries of macromolecular structures. As a Structural Biologist, you will play a crucial role in advancing our understanding of protein function, designing novel therapeutic strategies, and contributing to drug discovery pipelines. This role demands a strong foundation in structural biology principles, hands-on experience with various experimental methodologies, and the ability to interpret intricate data to drive meaningful scientific conclusions. We are looking for a proactive researcher who thrives in a collaborative, fast-paced environment and is passionate about translating fundamental research into tangible biological insights. If you are eager to apply your expertise to challenging projects with real-world implications, we encourage you to explore this exciting opportunity to shape the future of medicine and scientific discovery.
Key Responsibilities
- Design and execute experiments for the expression, purification, and characterization of challenging target proteins relevant to disease pathways.
- Determine high-resolution 3D structures of biological macromolecules using techniques such as X-ray crystallography, cryo-electron microscopy (cryo-EM), or NMR spectroscopy.
- Analyze and interpret structural data, integrating it with biochemical, biophysical, and functional data to gain deep insights into protein mechanism and function.
- Collaborate effectively with cross-functional teams including biochemists, cell biologists, computational chemists, and pharmacologists to advance research projects from conception to completion.
- Prepare detailed scientific reports, presentations, and contribute to scientific publications and patent applications.
- Maintain state-of-the-art laboratory equipment, ensuring optimal functionality and implementing best practices for structural biology workflows.
- Actively participate in scientific discussions, journal clubs, and contribute to the intellectual property development of the organization.
Required Skills
- PhD in Structural Biology, Biochemistry, Biophysics, or a closely related scientific field.
- Proficiency in protein expression and purification from various systems (e.g., E. coli, insect cells, mammalian cells).
- Demonstrated expertise in X-ray crystallography, including crystal growth, data collection, and structure determination and refinement.
- Strong analytical and problem-solving skills with the ability to interpret complex structural and biophysical data.
- Familiarity with industry-standard structural biology software packages (e.g., PHENIX, CCP4, PyMOL, Coot).
- Excellent written and verbal communication skills for presenting complex scientific information to diverse audiences.
- Ability to work both independently on specific tasks and collaboratively within a multidisciplinary team environment.
Preferred Qualifications
- Post-doctoral experience in an academic or industrial setting, ideally within pharmaceutical or biotechnology sectors.
- Hands-on experience with cryo-EM data collection, processing, and 3D reconstruction.
- Familiarity with NMR spectroscopy for protein structure determination and dynamics studies.
- In-depth knowledge of drug discovery principles and practical experience in structure-based drug design.
- Experience with automation and high-throughput screening technologies in protein science.
Perks & Benefits
- Competitive annual salary and comprehensive health, dental, and vision insurance package.
- Generous paid time off, including vacation, sick leave, and company-recognized holidays.
- 401(k) retirement savings plan with a substantial company match.
- Opportunities for continuous professional development, training, and attendance at scientific conferences.
- A dynamic, innovative, and collaborative work environment focused on scientific excellence.
- Access to state-of-the-art research facilities, cutting-edge instrumentation, and advanced computational resources.
- Relocation assistance for eligible candidates moving to the Tupelo area.
How to Apply
Interested candidates are invited to submit a detailed resume and a compelling cover letter outlining their research experience, specific expertise in structural biology techniques, and their interest in this pivotal role. Please click on the application link below to apply directly. We look forward to reviewing your qualifications and potentially welcoming you to a pioneering scientific team.
